Short communication: Detection of praziquantel resistance in schistosomes

Short communication: Detection of praziquantel resistance in schistosomes
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DOI:
10.1046/j.1365-3156.2000.00514.x
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发表时间:
2000-01-01
影响因子:
3.3
通讯作者:
Doenhoff, MJ
Doenhoff, MJ
中科院分区:
医学4区
文献类型:
--
作者:
Liang, YS;Coles, GC;Doenhoff, MJ

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提示一种简便、经济的检测吡喹酮耐药的方法。使用从感染者粪便中获得的虫卵或毛蚴;吡喹酮对毛蚴的影响;毛蚴在不同浓度吡喹酮中停止游动;通过加入一滴卢戈碘观察形态学变化。
Suggests a simple and economic assay to detect praziquantel resistance in schistosomes. Use of eggs or miracidia obtained from the fecal material of infected human; Effect of praziquantel on miracidia; Cessation of swimming of miracidia in different concentrations of praziquantel; Morphological changes observed by adding a drop of Lugol's iodine.