Sociodemographic risk factors for autism in a US metropolitan area
Sociodemographic risk factors for autism in a US metropolitan area
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DOI：
10.1007/s10803-006-0194-y
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发表时间：
2007-04-01
影响因子：
3.9
通讯作者：
Schendel, Diana
中科院分区：
文献类型：
--
作者：
Bhasin, Tanya Karapurkar;Schendel, Diana
本研究探讨了自闭症和社会人口因素之间的关联，整体和自闭症儿童和无精神发育迟滞（自闭症/MR和自闭症/无MR，分别）的亚组，进一步研究的关联在子分析儿童的来源的确认，以评估存在的确认偏差。在主要分析中，较高社会阶层的一个标志（较高的家庭收入中位数）与自闭症总体显著相关。较高的社会阶层（较高的母亲教育和较高的家庭收入中位数）的两个标志物显着相关的自闭症/无MR，但不相关的自闭症/MR。在亚组分析中，协会与社会阶层不同的确定来源。未来的研究应该考虑自闭症儿童的表型亚组，必须考虑潜在的确定偏差。
The present study examined the association between autism and sociodemographic factors, overall and in subgroups of children with autism with and without mental retardation (Autism/MR and Autism/No MR, respectively); the association was further examined in subanalyses by child's source of ascertainment to assess the presence of ascertainment bias. In the main analyses, one marker of higher social class (higher median family income) was significantly associated with autism overall. Both markers of higher social class (higher maternal education and higher median family income) were significantly associated with autism/no MR, but not associated with autism/MR. In the subanalyses, associations with social class varied by ascertainment source. Future studies should consider phenotypic subgroups of children with autism and must consider potential ascertainment bias.