Efficacy and Safety of Intra-Arterial Thrombolysis in Central Retinal Artery Occlusion
Efficacy and Safety of Intra-Arterial Thrombolysis in Central Retinal Artery Occlusion
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DOI：
10.1167/iovs.13-12952
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发表时间：
2013-11-01
影响因子：
4.4
通讯作者：
Jung, Cheolkyu
中科院分区：
文献类型：
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作者：
Ahn, Seong Joon;Kim, Jae Min;Jung, Cheolkyu
目的。探讨动脉内溶栓（IAT）治疗急性视网膜中央动脉闭塞（CRAO）的有效性和安全性。方法。对 101 名接受 IAT (n = 57) 或标准治疗 (ST; n = 44) 治疗的 CRAO 患者的记录进行了回顾性审查。 ST包括眼部按摩和降眼压药物。我们使用眼底镜和血管造影结果将 CRAO 分类为不完全（视力 [VA] 下降，伴有轻微视网膜水肿、轻微樱桃红斑）、次全（VA 严重降低、樱桃红斑、明显视网膜水肿）或完全（严重水肿、黄斑周小动脉闭塞、额外脉络膜血流中断）。将IAT组与ST组的1个月及最终最佳矫正视力（BCVA）进行比较。早期的 （
PURPOSE. To investigate the efficacy and safety of intra-arterial thrombolysis (IAT) for acute central retinal artery occlusion (CRAO).METHODS. Records from 101 CRAO patients treated with either IAT (n = 57) or standard treatment (ST; n = 44) were retrospectively reviewed. ST consisted of ocular massage and intraocular pressure-lowering agents. We used fundoscopic and angiographic findings to categorize CRAO as incomplete (diminished visual acuity [VA] with slight retinal edema, slight cherry-red spot), subtotal (severe VA reduction, cherry-red spot, distinct retinal edema), or total (massive edema, occluded perimacular arterioles, additional choroidal blood flow interruption). One-month and final best-corrected VA (BCVA) of the IAT group were compared with those of the ST group. Early (