MRI differentiation of cardiomyopathy showing left ventricular hypertrophy and heart failure: differentiation between cardiac amyloidosis, hypertrophic cardiomyopathy, and hypertensive heart disease
MRI differentiation of cardiomyopathy showing left ventricular hypertrophy and heart failure: differentiation between cardiac amyloidosis, hypertrophic cardiomyopathy, and hypertensive heart disease
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心肌病的 MRI 鉴别显示左心室肥厚和心力衰竭：心肌淀粉样变性、肥厚性心肌病和高血压性心脏病之间的鉴别
DOI：
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发表时间：
2013
影响因子：
2.1
通讯作者：
S. Kumita
中科院分区：
文献类型：
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作者：
Minako Takeda;Y. Amano;M. Tachi;Hitomi Tani;K. Mizuno;S. Kumita
目的评价MRI对心脏淀粉样变性(CA)、终末期肥厚型心肌病(HCM)和高血压性心脏病(HHD)的鉴别能力，这些疾病是导致左室肥厚(LVH)和心力衰竭的重要原因。比较三种疾病的心功能、心包或胸腔积液、晚期Gd强化(LGE)的程度和类型。结果6例CA、8例终末期HCM和6例HHD患者均可观察到心肌LGE。CA组LGE节段数明显多于HCM组和HHD组(P均<0.02)，且CA患者均表现为整体LGE。CA组、HCM组和HHD组在射血分数、舒张末和收缩末期容量指数方面均有显著差异(P均<0.05)。CA心包积液发生率明显高于HCM和HHD(P值分别为0.04和0.01)。结论MRI对鉴别CA、终末期HCM和HHD均有较高的鉴别诊断价值。
PurposeTo evaluate the capability of MRI to differentiate cardiac amyloidosis (CA), end-stage hypertrophic cardiomyopathy (HCM), and hypertensive heart disease (HHD), which are important etiologies of left ventricular hypertrophy (LVH) and heart failure.Materials and methodsWe enrolled 26 patients presenting with both LVH and heart failure: six with CA, nine with end-stage HCM, and 11 with HHD. Cardiac function, presence of pericardial or pleural effusion, and the extent and patterns of late gadolinium enhancement (LGE) were compared among the three diseases.ResultsMyocardial LGE was observed in all six CA patients, eight end-stage HCM patients, and six HHD patients. The number of LGE segments was significantly greater in CA than in HCM or HHD (p = 0.02 for both), and all patients with CA showed a global endocardial pattern of LGE. There were significant differences among CA, HCM, and HHD in ejection fraction and end-diastolic and end-systolic volume indices (p < 0.05 for all). Pericardial effusion was observed more frequently in CA than in HCM or HHD (p = 0.04 or 0.01, respectively).ConclusionMRI is valuable for distinguishing among CA, end-stage HCM, and HHD, all of which present with LVH and heart failure.
影响因子：
158.5
作者：
Kim, RJ;Wu, E;Judd, RM
通讯作者：
Judd, RM