Endocrine effects of meternal alcoholization: plasma and brain testosterone, dihydrotestosterone, estradiol, and corticosterone.
Endocrine effects of meternal alcoholization: plasma and brain testosterone, dihydrotestosterone, estradiol, and corticosterone.
复制标题
内醇化的内分泌影响：血浆和脑睾酮、二氢睾酮、雌二醇和皮质酮。
DOI：
--
复制
发表时间：
1980
期刊：
影响因子：
--
通讯作者：
J. Moore
中科院分区：
文献类型：
--
作者：
R. Kakihana;J. Butte;J. Moore
与喂食蔗糖的母鼠所产性别匹配的幼崽相比，母亲的乙醇消耗量与1- 2天大雄性大鼠大脑中双氢睾酮水平的降低有关。与此相反，大脑皮质酮水平显着增加时，从蔗糖喂养的控制相比，在乙醇喂养的动物的幼崽。脑和血浆雌二醇组间无差异。这些结果表明，母亲的乙醇消费可能会影响中枢神经系统和某些类固醇激素在后代的血浆水平。
Maternal ethanol consumption was associated with reduced levels of dihydrotestosterone in the brains of 1--2-day-old male rats when compared to those of sex-matched pups obtained from dames that were fed sucrose. In contrast, brain levels of corticosterone were increased significantly in the pups of ethanol-fed animals when compared to those from sucrose-fed controls. Brain and plasma estradiol did not differ between groups. These results suggest that maternal ethanol consumption may influence the central nervous system and plasma levels of certain steroidal hormones in the offspring.