Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes
Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes
复制标题
DOI：
10.1039/b901889a
复制
发表时间：
2009-01-01
影响因子：
4.9
通讯作者：
Neidle, Stephen
中科院分区：
文献类型：
--
作者：
Collie, Gavin;Reszka, Anthony P.;Neidle, Stephen
四链体RNA比它们的DNA对应物更不容易理解，但具有潜在的高生物学相关性。几个四链体结合配体与端粒RNA四链体的相互作用的报道，并与它们的结合类似的DNA四链体进行比较。
Quadruplex RNAs are less well understood than their DNA counterparts, yet of potentially high biological relevance. The interactions of several quadruplex-binding ligands with telomeric RNA quadruplexes are reported and compared with their binding to the analogous DNA quadruplexes.