The future of DNA sequence archiving.
The future of DNA sequence archiving.
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DOI：
10.1186/2047-217x-1-2
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发表时间：
2012-07-12
期刊：
影响因子：
9.2
通讯作者：
Birney E
中科院分区：
文献类型：
--
作者：
Cochrane G;Cook CE;Birney E
在国际核苷酸序列数据库协作下运行的档案目前保留所有提交的序列，但是全球序列产生速率的快速提高将很快需要差异化处理用于归档的DNA序列。在这里，我们提出了一个分级系统，在该系统中，基于测序的实验的易于再现，以及用于重新取证样品的相对可用性定义了应用于存储数据的有损压缩水平。
Archives operating under the International Nucleotide Sequence Database Collaboration currently preserve all submitted sequences equally, but rapid increases in the rate of global sequence production will soon require differentiated treatment of DNA sequences submitted for archiving. Here, we propose a graded system in which the ease of reproduction of a sequencing-based experiment and the relative availability of a sample for resequencing define the level of lossy compression applied to stored data.