What Does Nasal Cavity Size Tell us about Functional Nasal Airways?
What Does Nasal Cavity Size Tell us about Functional Nasal Airways?
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DOI：
10.3166/bmsap-2018-0011
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发表时间：
2019-04-01
影响因子：
--
通讯作者：
Heuze, Y.
中科院分区：
文献类型：
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作者：
Heuze, Y.
对干燥人类头骨的研究表明，鼻腔（NC）形态因生态地理因素而异。这些发现被一些作者用来解释尼安德特人的面部形态。然而，呼吸和空气调节功能主要由鼻气道（NA）执行，鼻气道由粘膜界定。本研究的目的是检验：（1）NC体积（V）和表面积与体积比（SA/ V）是否与NA对应物成正比;（2）男性NC和NA的测量值大于女性;（3）在NC上测量的一组界标的质心大小（CS）为NC V提供了可靠的代理。回顾性选择波尔多大学医院成人患者（N = 30）的CT（计算机断层扫描）图像。通过分割对应于功能体积的管腔来定义NA。通过将形成NC的骨界定的软组织添加到NA中来定义NC。记录NC骨上测量的16个标志点的坐标。NA与NC V的相关性较低，NA SA/V与NC SA/V无相关性。男性和女性NA和NC测量之间没有显着差异。NC V与NC CS之间的相关性较低。如果这些初步结果被证实，未来的研究，结果使用NC作为代理NA集中在空调和呼吸能量学可能需要重新解释。
Studies on dry human skulls have shown that nasal cavity (NC) morphology varies with eco-geographic factors. These findings have been used by some authors to interpret the facial morphology of Neanderthals. However, respiratory and air-conditioning functions are primarily carried out by the nasal airways (NA), which are delimited by mucosa. The aims of this study were to test whether: (1) NC volume (V) and surface-area-to-volume ratio (SA/ V) are proportional to NA counterparts; (2) measurements for male NC and NA are larger than in females; (3) the centroid size (CS) of a set of landmarks measured on NC provides a reliable proxy for NC V. Head CT (computed tomography) images of adult patients (N = 30) at the University Hospital of Bordeaux were selected retrospectively. NA were defined by segmenting the lumen corresponding to the functional volume. NC was defined by adding to NA the soft tissues delimited by the bones forming the NC. The coordinates of 16 landmarks measured on NC bones were recorded. A rather low correlation was found between NA and NC V while NA SA/V and NC SA/V were not correlated. No significant differences were found between male and female NA and NC measurements. A rather low correlation was found between NC Vand NC CS. If these preliminary results were to be confirmed by future studies, results using NC as a proxy for NA focusing on air-conditioning and respiratory energetics might need to be re-interpreted.