Change in antiepileptic drug prescription patterns for pregnant women with epilepsy over the years: Impact on pregnancy and fetal outcomes
Change in antiepileptic drug prescription patterns for pregnant women with epilepsy over the years: Impact on pregnancy and fetal outcomes
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DOI：
10.4103/ijp.ijp_78_19
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发表时间：
2019-03-01
影响因子：
2.4
通讯作者：
Kumar, Praveen
中科院分区：
文献类型：
--
作者：
Bansal, Ramandeep;Suri, Vanita;Kumar, Praveen
目的和目的：本研究的目的是：(1)确定在印度北部三级医疗机构接受治疗的癫痫女性（WWE）妊娠期间抗癫痫药物（AED）处方模式是否有变化；(2)确定AED处方模式的改变是否会改善WWE患者的胎儿和母体结局。患者和方法：本研究是对印度北部一家三级护理教学医院妇产科内科和外科疾病门诊WWE的记录进行回顾性分析。我们回顾性收集2011 - 2015年5年间所有患者的资料（A组）（n = 177），并将其与我们之前发表的1987-1994年的资料（B组）（n = 219）进行比较。结果：在单药治疗的女性中，A组(i)左乙拉西坦（LEV）的使用明显高于B组(P
AIMS AND OBJECTIVES: The objectives of the study were: (1) to determine if there is a change in pattern of antiepileptic drug (AED) prescription during pregnancy in women with epilepsy (WWE) attending a tertiary care institute in North India and (2) to determine if change in AED prescription pattern has resulted in improved fetal and maternal outcomes in WWE.PATIENTS AND METHODS: The current study was a retrospective analysis of records of WWE attending a medical and surgical disorder clinic of obstetrics and gynecology department of a tertiary care teaching hospital in North India. We retrospectively collected data of all the patients during the 5-year period from 2011 to 2015 (Group A) (n = 177) and compared it with our previously published data during the years 1987-1994 (Group B) (n = 219).RESULTS: There was significantly higher use of (i) levetiracetam (LEV) in Group A compared to Group B when women on monotherapy were compared (P