Interstitial Lung Disease Associated With the Idiopathic Inflammatory Myopathies What Progress Has Been Made in the Past 35 Years?
Interstitial Lung Disease Associated With the Idiopathic Inflammatory Myopathies What Progress Has Been Made in the Past 35 Years?
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DOI：
10.1378/chest.10-0180
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发表时间：
2010-12-01
期刊：
影响因子：
9.6
通讯作者：
Danoff, Sonye K.
中科院分区：
文献类型：
--
作者：
Connors, Geoffrey R.;Christopher-Stine, Lisa;Danoff, Sonye K.
间质性肺病通常与自身免疫性炎性肌病、皮肌炎和多发性肌炎相关，并且在这些病症中占显著的发病率和死亡率。自从最初描述炎性肌病和间质性肺病之间的关联以来的35年中，在诊断和治疗这种疾病方面已经取得了进展。关于发病机制和治疗方法仍有许多有待了解。本综述探讨了对这种复杂疾病理解的变化，突出了最近的进展和值得进一步研究的领域CHEST 2010，138（6）1464-1474。
Interstitial lung disease is commonly associated with the autoimmune inflammatory myopathies dermatomyositis and polymyositis and accounts for significant morbidity and mortality m these conditions In the 35 years since the association between inflammatory myopathy and interstitial lung disease was initially described, there has been progress in diagnosing and treating this disorder Nevertheless, there remains much about pathogenesis and therapeutics to be learned This review examines the changes in the understanding of this complex condition, highlighting recent advances and areas deserving of further study CHEST 2010, 138(6) 1464-1474