The effect of group aerobic exercise and T'ai chi on functional outcomes and quality of life for persons living with acquired immunodeficiency syndrome
The effect of group aerobic exercise and T'ai chi on functional outcomes and quality of life for persons living with acquired immunodeficiency syndrome
复制标题
DOI：
10.1089/acm.2005.11.1085
复制
发表时间：
2005-12-01
影响因子：
2.6
通讯作者：
Farrar, JT
中科院分区：
文献类型：
--
作者：
Galantino, ML;Shepard, K;Farrar, JT
目的：本研究旨在评估团体康复医学环境中两种干预措施的有效性，以确定感染人类免疫缺陷病毒（HIV）和/或获得性免疫缺陷综合征（AIDS）的艾滋病毒/艾滋病人群的长期护理策略和运动指南。设计：这是一项随机临床试验，调查太极拳（TC）和有氧运动（EX）对艾滋病患者的功能结果和生活质量（QOL）的影响。设置：两个门诊传染病诊所背景为中大西洋州。 受试者和干预：三十八 (38) 名晚期 HIV (AIDS) 受试者被随机分入三组之一：TC、EX 或对照组。实验组每周锻炼两次，持续 8 周。 结果测量：主要结果包括通过医疗结果简表 (MOS-HIV) 和灵性幸福量表 (SWB) 测量的生活质量。功能测量包括用于平衡的功能伸展（FR）、用于灵活性的坐姿和伸展（SR）以及用于耐力的仰卧起坐（SU）测试。身体表现测试（PPT）用于确定整体功能，情绪状态概况（POMS）用于评估心理变化。为了考虑患者对这些测量的解释，从受试者的期刊、焦点小组和非参与观察中收集了定性数据。结果：三十八 (38) 名受试者纳入数据分析：TC 组 13 名，EX 组 13 名，对照组 12 名。协方差分析结果显示，运动组的整体功能测量有显着变化（p < 0.001）。 MOS-HIV 在整体健康分量表上显示出显着差异 (p = 0.04)。 POMS 在困惑-困惑 (p = 0.000) 和紧张-焦虑 (p = 0.005) 方面显示出时间的显着主效应。定性数据中出现了三个主要主题，包括：积极的身体变化、增强的心理应对能力和改善的社交互动。结论：本研究表明 TC 和 EX 可以改善生理参数、功能结果和生活质量。团体干预为慢性艾滋病的管理提供了社会化环境。这项研究支持需要进行更多研究来调查其他类型的团体锻炼对该人群的影响。这项研究为更大规模的随机对照试验奠定了基础，以检验团体锻炼的潜在短期和长期影响，这可能有助于治疗晚期艾滋病毒。需要进一步的研究来评估对艾滋病毒人群来说可行、安全且具有成本效益的额外运动干预措施。
Objective: This study aimed to assess the usefulness of two interventions in a group rehabilitation medicine setting to determine strategies and exercise guidelines for long-term care of the HIV/AIDS population with human immunodeficiency virus (HIV) and/or acquired immunodeficiency syndrome (AIDS).Design: This was a randomized clinical trial investigating the effects of tai chi (TC) and aerobic exercise (EX) on functional outcomes and quality of life (QOL) in patients with AIDS.Setting: Two outpatient infectious disease clinics in a Mid-Atlantic state were the setting.Subjects and intervention: Thirty-eight (38) subjects with advanced HIV (AIDS) were randomized to one of three groups: TC, EX, or control. Experimental groups exercised twice weekly for 8 weeks.Outcome measures: The primary outcomes included QOL as measured by the Medical Outcomes Short Form (MOS-HIV) and Spirituality Well-Being Scale (SWB). Functional measures included the functional reach (FR) for balance, sit and reach (SR) for flexibility, and sit-up (SU) test for endurance. The physical performance test (PPT) was used to determine overall function, and the Profile of Mood States (POMS) was used to evaluate psychologic changes. To consider the patients' explanations for these measurements, qualitative data were collected from subjects' journals, focus groups, and nonparticipant observation.Results: Thirty-eight (38) subjects were included in data analysis: 13 in the TC group, 13 in the EX group, and 12 in the control group. Results of analysis of covariance showed significant changes in the exercise groups in overall functional measures (p < 0.001). The MOS-HIV showed a significant difference on the subscale of overall health (p = 0.04). The POMS showed significant main effect for time in confusion-bewilderment (p = 0.000) and tension-anxiety (p = 0.005). Three dominant themes emerged from the qualitative data, including: positive physical changes, enhanced psychologic coping, and improved social interactions.Conclusions: This study shows that TC and EX improve physiologic parameters, functional outcomes, and QOL. Group intervention provides a socialization context for management of chronic HIV disease. This study supports the need for more research investigating the effect of other types of group exercise for this population. This study sets the stage for a larger randomized controlled trial to examine the potential short- and long-term effects of group exercise that may prove beneficial in the management of advanced HIV disease. Further research is warranted to evaluate additional exercise interventions that are accessible, safe, and cost-effective for the HIV population.