Prevalence of HIV infection and risk behaviors among younger and older injecting drug users in the United States, 2009.
Prevalence of HIV infection and risk behaviors among younger and older injecting drug users in the United States, 2009.
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DOI：
10.1007/s10461-013-0660-4
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发表时间：
2014-04
影响因子：
4.4
通讯作者：
Paz-Bailey G
中科院分区：
文献类型：
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作者：
Broz D;Pham H;Spiller M;Wejnert C;Le B;Neaigus A;Paz-Bailey G
这项研究比较了年轻和老年注射吸毒者 (IDU) 之间的 HIV 血清流行率和危险行为。 2009 年国家艾滋病毒行为监测系统对年龄≥18 岁的注射吸毒者进行了访谈。使用 GEE 回归，我们评估了年轻（18-29 岁）和老年（≥30 岁）IDU 的特征，以及与过去 12 个月共用注射器和无保护性行为（阴道/肛交）相关的因素。在 10,090 名参与者中，10% 较为年轻。年轻注射吸毒者中的 HIV 血清流行率低于老年注射吸毒者（4% vs. 10%，p = 0.001）。年轻的注射吸毒者更有可能 (p ≤ 0.002) 是非黑人种族/族裔，报告家庭收入较高、无家可归、被捕、共用注射器和无保护性行为。在多变量模型中，年龄仍然与共用注射器（aPR = 1.14，95% CI1.07–1.22）和无保护性行为（aPR = 1.10，95% CI1.06–1.14）相关（p < 0.001）。尽管年轻的注射吸毒者的艾滋病毒感染率较低，但他们的行为使他们感染艾滋病毒的风险增加，并可能导致艾滋病毒在易感人群中迅速传播。
This study compared HIV sero-prevalence and risk behaviors between younger and older injecting drug users (IDUs). IDUs aged ≥18 years were interviewed for the 2009 National HIV Behavioral Surveillance System. Using GEE regression, we assessed characteristics of younger (18–29 years) and older (≥30 years) IDUs, and factors associated with past 12-month receptive syringe sharing and unprotected sex (vaginal/anal). Of 10,090 participants, 10 % were younger. HIV sero-prevalence was lower among younger than older IDUs (4 vs. 10 %, p = 0.001). Younger IDUs were more likely (p ≤ 0.002) to be non-black race/ethnicity, report higher household income, homelessness, being arrested and to engage in receptive syringe sharing and unprotected sex. In multivariable models, age remained associated (p < 0.001) with receptive syringe sharing (aPR = 1.14, 95 % CI1.07–1.22) and unprotected sex (aPR = 1.10, 95 % CI1.06–1.14). Although younger IDUs had lower HIV prevalence, their behaviors place them at increased risk of HIV infection and could lead to a rapid spread in this susceptible population.