Cotard syndrome in semantic dementia.
Cotard syndrome in semantic dementia.
复制标题
语义痴呆中的科塔尔综合征。
DOI：
10.1016/j.psym.2011.06.004
复制
发表时间：
2011
期刊：
影响因子：
3.4
通讯作者：
Ramirez-Bermudez,Jesus
中科院分区：
文献类型：
--
作者：
Mendez,MarioF;Ramirez-Bermudez,Jesus
研究背景语义性痴呆是一种神经退行性疾病，其特征是对词语或概念失去意义。语义性痴呆可以为内容特异性妄想的机制提供潜在的见解。目的报道一例罕见的语义性痴呆伴科塔尔综合征，是一种以虚无或自我否定为特征的妄想。方法对语义性痴呆的语义缺陷和其他特征进行评估，并与患者的Cotard综合征进行比较。结果A女士产生了一种错觉，认为她正在消瘦和死亡。这发生在她失去了对身体不适和感觉以及这些感觉来源的器官的知识之后。她的虚无主义信仰似乎来自于她对自己身体感觉的误解。结论这一独特的病人表明，Cotard综合征的一个机制是难以解释内部疼痛和感觉的性质和来源。我们认为，失去对自己身体的语义知识可能会导致虚无主义或死亡的错觉。
Background Semantic dementia is a neurodegenerative disorder characterized by the loss of meaning of words or concepts. semantic dementia can offer potential insights into the mechanisms of content-specific delusions. Objective The authors present a rare case of semantic dementia with Cotard syndrome, a delusion characterized by nihilism or self-negation. Method The semantic deficits and other features of semantic dementia were evaluated in relation to the patient's Cotard syndrome. Results Mrs. A developed the delusional belief that she was wasting and dying. This occurred after she lost knowledge for her somatic discomforts and sensations and for the organs that were the source of these sensations. Her nihilistic beliefs appeared to emerge from her misunderstanding of her somatic sensations. Conclusion This unique patient suggests that a mechanism for Cotard syndrome is difficulty interpreting the nature and source of internal pains and sensations. We propose that loss of semantic knowledge about one's own body may lead to the delusion of nihilism or death.