Regions of the MPFC differentially tuned to social and nonsocial affective evaluation
Regions of the MPFC differentially tuned to social and nonsocial affective evaluation
复制标题
DOI：
10.3758/cabn.7.4.309
复制
发表时间：
2007-12-01
影响因子：
2.9
通讯作者：
Fiske, Susan T.
中科院分区：
文献类型：
--
作者：
Harris, Lasana T.;McClure, Samuel M.;Fiske, Susan T.
内侧前额叶皮层（MPFC）在社会认知和奖励任务中可靠地激活。这项研究为每一个不同的领域定位。在一个缓慢的事件相关设计中，参与者对图片中的积极或消极的人和物体进行评价（积极/消极）或社会（人/不是人）判断。在前喙区（arMPFC）的活动显着大于积极的人比消极的人，但没有显示出效价效应的对象，这是真实的，无论判断任务。这表明arMPFC与社会效价有关。然而，有趣的是，没有区域的MPFC被发现是独立的社会信息的反应价。一个区域的利益分析的前扣带皮层（pACC），以前涉及奖励处理，表现出敏感性的所有刺激的效价，无论是人还是物体，跨任务。情感评估可以是MPFC的一般功能，其中一些区域被调谐到更具体的信息域（例如，社会）比其他人。
The medial prefrontal cortex (MPFC) reliably activates in social cognition and reward tasks. This study locates distinct areas for each. Participants made evaluative (positive/negative) or social (person/not a person) judgments of pictured positive or negative people and objects in a slow event-related design. Activity in an anterior rostral region (arMPFC) was significantly greater for positive than for negative persons but did not show a valence effect for objects, and this was true regardless of the judgment task. This suggests that the arMPFC is tuned to social valence. Interestingly, however, no regions of the MPFC were found to be responsive to social information independently of valence. A region-of-interest analysis of the paraanterior cingulate cortex (pACC), previously implicated in reward processing, demonstrated sensitivity to the valence of all stimuli, whether persons or objects, across tasks. Affective evaluation may be a general function of the MPFC, with some regions being tuned to more specific domains of information (e.g., social) than are others.