Influence of Material Deprivation on Clinical Outcomes Among People Living with HIV in High-Income Countries: A Systematic Review and Meta-analysis.
Influence of Material Deprivation on Clinical Outcomes Among People Living with HIV in High-Income Countries: A Systematic Review and Meta-analysis.
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DOI：
10.1007/s10461-021-03551-y
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发表时间：
2022-06
影响因子：
4.4
通讯作者：
Ward, Helen
中科院分区：
文献类型：
--
作者：
Papageorgiou, Vasiliki;Davies, Bethan;Cooper, Emily;Singer, Ariana;Ward, Helen
关键词：
尽管艾滋病毒治疗和护理取得了进展，但差距仍然存在，一些人没有充分受益于艾滋病毒护理连续性的改善。我们进行了系统评价，以探讨高收入国家社会决定因素与艾滋病毒治疗结果（病毒抑制和治疗依从性）之间的关联。在暴露测量结果一致的情况下进行了随机效应荟萃分析。我们确定了 83 项符合纳入条件的观察性研究。与物质匮乏相关的社会决定因素被确定为教育、就业、粮食安全、住房、收入、贫困/剥夺、社会经济地位/地位和社会阶层；然而，它们的测量和定义在不同的研究中有所不同。我们的审查表明，艾滋病毒护理连续体中持续存在健康的社会梯度；报告物质匮乏的艾滋病毒感染者不太可能受到病毒学抑制或坚持使用抗逆转录病毒药物。未来的研究应该使用生态社会方法来探索生命历程中的这些相互作用，以帮助提出因果路径。在线版本包含可在 10.1007/s10461-021-03551-y 获取的补充材料。
Despite developments in HIV treatment and care, disparities persist with some not fully benefiting from improvements in the HIV care continuum. We conducted a systematic review to explore associations between social determinants and HIV treatment outcomes (viral suppression and treatment adherence) in high-income countries. A random effects meta-analysis was performed where there were consistent measurements of exposures. We identified 83 observational studies eligible for inclusion. Social determinants linked to material deprivation were identified as education, employment, food security, housing, income, poverty/deprivation, socioeconomic status/position, and social class; however, their measurement and definition varied across studies. Our review suggests a social gradient of health persists in the HIV care continuum; people living with HIV who reported material deprivation were less likely to be virologically suppressed or adherent to antiretrovirals. Future research should use an ecosocial approach to explore these interactions across the lifecourse to help propose a causal pathway. The online version contains supplementary material available at 10.1007/s10461-021-03551-y.
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