Primary liver-cell carcinoma with a protracted clinical course. Report of a case.
Primary liver-cell carcinoma with a protracted clinical course. Report of a case.
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具有长期临床病程的原发性肝细胞癌。
DOI：
10.1001/jama.1963.73700150014022
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发表时间：
1963
期刊：
影响因子：
--
通讯作者：
D. Hunt
中科院分区：
文献类型：
--
作者：
D. Hunt
原发性肝癌被认为是一种迅速致命的疾病。这一流行概念的基础是报告病例的临床病程统一较短。本文的目的是报告一例原发性肝细胞癌的年轻成年男性谁存活5年未经治疗。一例28岁男性泥水匠于1962年1月20日到帕洛阿尔托-斯坦福医院检查腹水，积水量超过2周。入院前5年，患者在体检时发现腹部有一个压痛性肿块，估计直径为9cm。肿块被认为位于肝脏左叶。没有肝炎、酒精中毒或肝毒素暴露史。当时所做的实验室检查包括正常的白细胞计数和差异。精华液
PRIMARY CARCINOMA of the liver has been described as a rapidly fatal disease. The basis for this prevailing concept has been the uniformly short clinical course in reported cases. The purpose of this paper is to report a case of primary liver-cell carcinoma in a young adult male who survived 5 yr without treatment. Report of a Case A 28-yr-old male plasterer entered the Palo Alto-Stanford Hospital on Jan 20, 1962, for evaluation of ascites which had accumulated over a 2-week period. Five years prior to admission, the patient had noted a tender epigastric mass that was estimated to be 9 cm in diameter on physical examination. The mass was thought to be located in the left lobe of the liver. There was no history of hepatitis, alcoholism, or exposure to hepatotoxins. Laboratory tests done at that time included a normal white blood cell count and differential. The serum