Copper(II)-Promoted C-C Bond Formation by Oxidative Coupling of Two C(sp3)-H Bonds Adjacent to Carbonyl Group to Construct 1,4-Diketones and Tetrasubstituted Furans
Copper(II)-Promoted C-C Bond Formation by Oxidative Coupling of Two C(sp3)-H Bonds Adjacent to Carbonyl Group to Construct 1,4-Diketones and Tetrasubstituted Furans
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DOI：
10.1002/ejoc.201403274
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发表时间：
2015-02-01
影响因子：
2.8
通讯作者：
Wang, Yong-Qiang
中科院分区：
文献类型：
--
作者：
Mao, Shuai;Gao, Ya-Ru;Wang, Yong-Qiang
铜(II)促进了C-C键的形成，这是由两个与一个羰基相邻的C(sp(3))-H键偶联而成的。该方案为合成2，3-二取代1，4-二酮和四取代呋喃提供了一种简单有效的方法。该方法具有底物范围宽、官能团容忍度高的特点。
The copper(II)-promoted C-C bond formation from the coupling of two C(sp(3))-H bonds that are adjacent to a carbonyl group was achieved. This protocol offers a simple and efficient approach to 2,3-disubstituted 1,4-diketones and tetrasubstituted furans. This method features a wide substrate scope and high functional group tolerance.