Development of novel biosensor enzyme electrodes: Glucose oxidase multilayer arrays immobilized onto self‐assembled monolayers on electrodes
Development of novel biosensor enzyme electrodes: Glucose oxidase multilayer arrays immobilized onto self‐assembled monolayers on electrodes
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DOI：
10.1002/adma.19930051206
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发表时间：
1993-12
影响因子：
29.4
通讯作者：
I. Willner;A. Riklin;Benjamin Shoham;Dalia Rivenzon;E. Katz
中科院分区：
文献类型：
--
作者：
I. Willner;A. Riklin;Benjamin Shoham;Dalia Rivenzon;E. Katz
电流型生物传感器是基于酶的氧化还原位点和电极之间的电子传递通信而发展起来的。这些需要表现出长程电子转移特性的酶的良好组织网络。描述了一种酶电极，其由在金电极上自组装的官能化硫醇单层上组织的葡萄糖氧化酶网络组成。蛋白质阵列支持与电极的电通信，并且所得的组装体可以用作葡萄糖生物传感器。
Amperometric biosensorsunder development are based on electron transfer communication between enzyme redox sites and electrodes. These require well‐organized networks of enzymes exhibiting long‐range electron transfer properties. An enzyme electrode is described that consists of glucose oxidase networks organized on a self‐assembled monolayer of functionalized thiols on gold electrodes. The protein array supports electrical communication with the electrode, and the resulting assembly can be used as a glucose biosensor.