SPEECH PAUSE TIME AS A METHOD FOR THE EVALUATION OF PSYCHOMOTOR RETARDATION IN DEPRESSIVE-ILLNESS
SPEECH PAUSE TIME AS A METHOD FOR THE EVALUATION OF PSYCHOMOTOR RETARDATION IN DEPRESSIVE-ILLNESS
复制标题
DOI：
10.1192/bjp.146.5.535
复制
发表时间：
1985-01-01
影响因子：
10.5
通讯作者：
MENDLEWICZ, J
中科院分区：
文献类型：
--
作者：
HOFFMANN, GMA;GONZE, JC;MENDLEWICZ, J
精神运动性迟缓对于一些抑郁症患者来说很重要。计数测试期间的言语停顿时间（SPT）与抑郁症患者和对照组的反应时间相关。它还与根据威德洛赫量表测量的整体精神运动迟缓相关。与对照组和非迟发型抑郁症患者相比，单相抑郁症患者以及迟发型抑郁症患者的 SPT 有所增加。对照组的 SPT 昼夜变化，但抑郁症受试者的 SPT 没有变化。它与抑郁症的生物标志物（快速眼动睡眠潜伏期和地塞米松抑制试验）无关。然而，在抗抑郁化疗的临床改善过程中，它确实缩短了。
Psychomotor retardation is important in some depressed patients. Speech pause time (SPT) during a counting test correlated with the reaction time of both depressed patients and controls. It also correlated with global psychomotor retardation measured on Widlocher''s scale. Increased SPT was demonstrated in unipolar depressives, and also in retarded depressives as a group when compared with controls and with non-retarded depressives. SPT varied diurnally in controls, but not in depressed subjects. It did not correlate with biological markers of depression (REM (rapid eye movement) sleep latency and the dexamethasone suppression test). It did, however, shorten during clinical improvement with antidepressant chemotherapy.