Accounting for Time: Circadian Rhythms in the Time of COVID-19
Accounting for Time: Circadian Rhythms in the Time of COVID-19
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DOI：
10.1177/0748730420953335
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发表时间：
2020-09-02
影响因子：
3.5
通讯作者：
FitzGerald, Garret A.
中科院分区：
文献类型：
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作者：
Sengupta, Shaon;Brooks, Thomas G.;FitzGerald, Garret A.
COVID-19 大流行需要跨学科的新颖方法和协作努力。众所周知，我们的生理机能和对病原体的反应的各个方面都受到严格的时钟控制。然而，昼夜节律生物学融入我们的临床和研究实践仍在不断发展。通过对英国生物银行的文献和原始分析的重点回顾，我们讨论了昼夜节律生物学如何为我们在这一流行病中的诊断和治疗策略提供信息。
The COVID-19 pandemic has necessitated novel approaches and collaborative efforts across multiple disciplines. It is known that various aspects of our physiology and response to pathogens are under tight clock control. However, the assimilation of circadian biology into our clinical and research practices is still evolving. Using a focused review of the literature and original analyses of the UK Biobank, we discuss how circadian biology may inform our diagnostic and therapeutic strategies in this pandemic.