Underactive bladder in women: is there any evidence?
Underactive bladder in women: is there any evidence?
复制标题
女性膀胱功能低下：有证据吗？
DOI：
10.1097/mou.0000000000000280
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发表时间：
2016
影响因子：
2.5
通讯作者：
Reynolds,WStuart
中科院分区：
文献类型：
--
作者：
Cohn,JoshuaA;Brown,ElizabethT;Kaufman,MelissaR;Dmochowski,RogerR;Reynolds,WStuart
膀胱活动不足（UAB）是一种临床症状复杂，最近才获得承认作为临床诊断。由于缺乏对UAB定义的共识，限制了其在临床实践中的识别和诊断。本综述的目的是：目前现有的定义UAB，审查最近的数据有关的临床和尿动力学诊断的条件，并检查最新的假设，其病理生理学，重点是妇女。将UAB定义为临床综合征的共识正在进行中。与UAB相关的症状，如尿流微弱、用力排尿和尿潴留病史，与尿动力学逼尿肌活动不足密切相关，常发生在老年女性中。除了衰老之外，UAB可能是多种促成病理状况（如糖尿病和缺血性疾病）的终末期。在某些女性中，UAB可能是由膀胱过度活动症进展为UAB引起的。现有证据支持女性UAB是一种综合症状，其临床和病理生理特征与其他下尿路相关临床疾病不同。临床和尿动力学诊断参数的共识定义对于更广泛地认识UAB至关重要。
Underactive bladder (UAB) is a clinical symptom complex only recently gaining recognition as a clinical diagnosis. Lack of consensus agreement on a definition of UAB has limited its recognition and diagnosis in clinical practice. The purposes of this review are to: present existing definitions of UAB, review recent data regarding clinical and urodynamic diagnosis of the condition, and examine up-to-date hypotheses regarding its pathophysiology, with a focus on women. The process to develop a consensus definition for UAB as a clinical symptom complex is ongoing. Symptoms associated with UAB, such as weak stream, straining to void, and history of urinary retention are well correlated to detrusor underactivity on urodynamics, which frequently develops in elderly women. In addition to aging, UAB may be the end stage of a variety of contributing pathologic conditions such as diabetes and ischemic disease. In some women, UAB may result from a progression from overactive bladder to UAB. Existing evidence supports UAB in women as a symptom complex with a clinical and pathophysiologic profile distinguishable from other lower urinary tract-associated clinical conditions. Consensus definitions of clinical and urodynamic diagnostic parameters will be essential to more widespread recognition of UAB.