Recent Developments in the Epidemiology of Bipolar Disorder in Adults and Children: Magnitude, Correlates, and Future Directions
Recent Developments in the Epidemiology of Bipolar Disorder in Adults and Children: Magnitude, Correlates, and Future Directions
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DOI：
10.1111/j.1468-2850.2009.01152.x
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发表时间：
2009-06-01
影响因子：
5.8
通讯作者：
Pato, Michael
中科院分区：
文献类型：
--
作者：
Merikangas, Kathleen R.;Pato, Michael
在过去十年中，人们越来越多地认识到双相情感障碍I和II(DSM-IV)对个人和社会的巨大影响。据估计，双相情感障碍的残疾调整寿命年数超过所有癌症和原发神经疾病，如癫痫和阿尔茨海默病，主要是因为其发病早和终生慢性(《世界卫生报告》，2002年)。使用当代诊断标准的众多国际流行病学调查的结果加强了双相情感障碍在具有代表性的普通人群样本中的规模、相关性和后果的证据基础。流行病学研究还表明，临床样本和社区样本在人口因素、合并症、发病模式、严重程度、治疗利用和反应方面存在差异。本文的目的是(A)通过对DSM-IV双相情感障碍在普通人群中的全面回顾，总结双相情感障碍在成人和儿童中的流行程度；(B)在社区调查中描述双相情感障碍的危险因素和相关因素；以及(C)描述双相情感障碍流行病学领域的未来方向。
During the past decade, there has been increasing recognition of the dramatic personal and societal impact of bipolar disorder I and II (DSM-IV). The estimated disability-adjusted life years of bipolar disorder outrank all cancers and primary neurologic disorders, such as epilepsy and Alzheimer's disease, primarily because of its early onset and chronicity across the lifespan (World Health Report, 2002). The results of numerous international epidemiologic surveys using contemporary diagnostic criteria have strengthened the evidence base on the magnitude, correlates, and consequences of bipolar disorder in representative samples of the general population. Epidemiologic research has also demonstrated the differences between clinical and community samples in terms of demographic factors, comorbidity, patterns of onset, severity, treatment utilization, and response. The aims of this article are (a) to summarize the magnitude of the prevalence of bipolar disorder in adults and children through a comprehensive review of DSM-IV bipolar disorder in the general population; (b) to describe the risk factors and correlates of bipolar disorder in community surveys; and (c) to describe the future directions for the field of epidemiology of bipolar disorder.