The spectrum of vascular involvement in giant-cell arteritis: clinical consequences of detrimental vascular remodelling at different sites
The spectrum of vascular involvement in giant-cell arteritis: clinical consequences of detrimental vascular remodelling at different sites
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DOI：
10.1111/j.1600-0463.2009.02471.x
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发表时间：
2009-06-01
期刊：
影响因子：
2.8
通讯作者：
Garcia-Martinez, Ana
中科院分区：
文献类型：
--
作者：
Cid, Maria C.;Prieto-Gonzalez, Sergio;Garcia-Martinez, Ana
尽管在文献中反复报道，但直到最近几年，巨细胞动脉炎累及颅外一直被认为是轶事。新的或改进的成像技术的出现，以及对这些患者更密切的随访和他们预期寿命的增加，开始强调GCA累及颅外的临床影响可能比以前认为的更相关。这篇综述的重点是通过病理和影像学研究报道的GCA的血管受累程度，以及不同血管区域不完全血管重塑的临床后果。
Although repeatedly reported in the literature, the extracranial involvement by giant-cell arteritis has been considered anecdotal until recent years. The emergence of new or improved imaging techniques along with a closer follow-up of these patients and their increase in life expectancy are beginning to underline that the clinical impact of extracranial involvement by GCA may be more relevant than previously thought. This review focuses on the extent of vascular involvement in GCA as reported by pathology and imaging studies as well as the clinical consequences of imperfect vascular remodelling in various vascular territories.