SPERMATOGENESIS IN THE IMMATURE MOUSE PROCEEDS FASTER THAN IN THE ADULT
SPERMATOGENESIS IN THE IMMATURE MOUSE PROCEEDS FASTER THAN IN THE ADULT
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DOI：
10.1111/j.1365-2605.1982.tb00257.x
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发表时间：
1982-01-01
影响因子：
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通讯作者：
DEROOIJ, DG
中科院分区：
文献类型：
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作者：
KLUIN, PM;KRAMER, MF;DEROOIJ, DG
在正常小鼠（Cpb-N 品系）的切片和管状整体睾丸切片中研究了与动物年龄相关的生精细胞类型的首次出现，最多 34 天。第一个中间精原细胞和细线精母细胞分别在第 4 天和第 7 天出现。研究发现，如果精子发生以成人速度进行，后续类型的生精细胞出现的时间比预期的要早。 [3H]胸苷标记研究表明，在给定的时间间隔内，未成熟小鼠的精母细胞和精子细胞发育成比成年小鼠更高级的细胞类型。标记研究和细胞关联始终与成年小鼠相同的观察结果表明，年轻小鼠的精原细胞、精母细胞和精细胞的加速速率是相同的。在 10 至 30 天的年龄间隔期间生精上皮周期的平均持续时间。为 7.51 pL 0.10 天，而成人为 8.61 pL 0.08。它逐渐增加到成人水平，在第 33 天和第 56 天之间达到 8.45 pL 0.17 天的值。
The first appearance of spermatogenic cell types related to the age of the animal was studied in sections and tubular whole mounts of testes of normal mice (Cpb‐N strain) up to 34 days p.p. The first intermediate spermatogonia and leptotene spermatocytes were seen at days 4 and 7 p.p., respectively. It was found that the subsequent types of spermatogenic cells appear earlier than could be expected if spermatogenesis was to proceed at adult speed. [3H]thymidine labelling studies revealed that within a given interval of time, spermatocytes and spermatids in immature mice develop into more advanced cell types than in adults. The labelling studies and the observation that the cellular associations are always identical to those in the adult, indicate that the rate of acceleration in young mice is the same for spermatogonia, spermatocytes and spermatids. The mean duration of the cycle of the seminiferous epithelium during the age interval of 10 to 30 days p.p. is 7.51 pL 0.10 days, compared to 8.61 pL 0.08 in the adult. It increases gradually towards the adult level, reaching the value of 8.45 pL 0.17 days between days 33 and 56 p.p.