Rod sensitivity relative to cone sensitivity in retinitis pigmentosa.
Rod sensitivity relative to cone sensitivity in retinitis pigmentosa.
复制标题
色素性视网膜炎中视杆细胞敏感性相对于视锥细胞敏感性。
DOI：
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发表时间：
1979
影响因子：
4.4
通讯作者：
D. Finkelstein
中科院分区：
文献类型：
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作者：
R. Massof;D. Finkelstein
本研究评估色素性视网膜炎患者视杆敏感性相对于视锥敏感性。从绝对阈值的周边测量到长波长和短波长的刺激，我们发现结果可以用三种不同的方式来表征。对于一组患者来说，在视野的所有部分似乎只有锥体功能存在。另一组患者，尽管绝对灵敏度损失很大，但视杆敏感度仍超过视锥敏感度，至少超出正常因子，提示视杆和视锥敏感度同时损失。对于第三组患者，中央视网膜阈值似乎主要由视锥决定，中外周视网膜阈值由视杆和视锥功能的复合决定，远外周阈值主要由视杆决定。不同组的阈值结果代表不同的疾病机制，而不是单一疾病进程的不同阶段。
The present study evaluates rod sensitivity relative to cone sensitivity in retinitis pigmentosa patients. From perimetric measures of absolute thresholds to long- and short-wavelength stimuli, we find the results can be characterized in three different ways. For one group of patients it appears that only cone function is present in all parts of the visual field. For another group of patients, despite large losses in absolute sensitivity, rod sensitivity still exceeds cone sensitivity by at least the normal factor, suggesting concomitant rod and cone sensitivity losses. For a third group of patients it appears that central retinal thresholds are determined primarily by cones, midperipheral retinal thresholds determined by a composite of rod and cone function, and far- peripheral thresholds determined predominately by rods. The argument is put forward that the different groups of threshold results represent different disease mechanisms rather than different stages in the progression of a single disease process.