Endoscopic resection of early gastric cancer treated by guideline and expanded National Cancer Centre criteria
Endoscopic resection of early gastric cancer treated by guideline and expanded National Cancer Centre criteria
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DOI：
10.1002/bjs.7033
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发表时间：
2010-06-01
影响因子：
9.6
通讯作者：
Oda, I.
中科院分区：
文献类型：
--
作者：
Gotoda, T.;Iwasaki, M.;Oda, I.
背景：国家癌症中心(NCC)最近扩大了早期胃癌(EGC)患者的内窥镜切除标准。这项研究比较了根据指南标准接受内窥镜治疗的EGC患者和根据扩展标准接受治疗的患者的长期结果。方法：1999年1月至2005年12月接受根治性内窥镜切除的EGC患者的基线和结果数据来自电子病历。结果：在1485例根治性切除患者中，635例(42.8%)根据传统标准进行了切除，625例(42.1%)根据扩展标准进行了切除。两组患者的总存活率没有显著差异。结论：按照扩展标准接受治疗的患者与按照指南标准接受治疗的患者具有相似的长期存活率和预后。
Background: Criteria for endoscopic resection in patients with early gastric cancer (EGC) have been expanded recently by the National Cancer Centre (NCC). This study compared long-term outcomes in patients with EGC who underwent endoscopic treatment according to guideline criteria with those treated according to expanded criteria.Methods: Baseline and outcome data from patients undergoing curative endoscopic resection for EGC between January 1999 and December 2005 were collected from electronic medical records. Survival time hazard ratios and 95 per cent confidence intervals were calculated using the Cox proportional hazards model.Results: Of 1485 patients who had a curative resection, 635 (42.8 per cent) underwent resection according to traditional criteria and 625 (42.1 per cent) according to expanded criteria. There was no significant difference in overall survival between the groups.Conclusion: Patients who have treatment following the expanded criteria have similar long-term survival and outcomes to those treated according to guideline criteria.