Hydrops foetalis caused by anti‐Mur in first pregnancy – a case report

Hydrops foetalis caused by anti‐Mur in first pregnancy – a case report
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DOI:
10.1046/j.1365-3148.2002.00394.x
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发表时间:
2002-10
影响因子:
1.5
通讯作者:
Kang-Hsi Wu;Jan‐Gowth Chang;M. Lin;M. Shih;Hung-Chih Lin;C. C. Lee-C.;C. Peng;C. Tsai
Kang-Hsi Wu;Jan‐Gowth Chang;M. Lin;M. Shih;Hung-Chih Lin;C. C. Lee-C.;C. Peng;C. Tsai
中科院分区:
医学4区
文献类型:
--
作者:
Kang-Hsi Wu;Jan‐Gowth Chang;M. Lin;M. Shih;Hung-Chih Lin;C. C. Lee-C.;C. Peng;C. Tsai

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抗Mia是台湾人群中最常见的具有潜在临床意义的同种异体抗体。Mi.III型在高加索人中很少见,但在各种东方人群中发病率很高。我们描述了一个没有输血史的产妇,在妊娠28周有积水的胎儿。胎儿血红蛋白为4·4 g dL−1,直接抗球蛋白试验阳性。经宫内血管内输血,婴儿健康出院。
Summary Anti‐‘Mia’ is the most common alloantibody of potential clinical significance in the Taiwanese population. The Mi.III phenotype is rare among Caucasians but has a high incidence in various Oriental populations. We describe a nulliparous woman with no history of transfusions, who had hydrops foetalis at 28 weeks gestation. Foetal haemoglobin was 4·4 g dL−1, and a positive direct antiglobulin test was positive in the foetal blood. Intrauterine intravascular transfusion was given, and the baby was discharged healthy.