Accelerated cardiac T2 mapping using breath-hold multiecho fast spin-echo pulse sequence with k-t FOCUSS.
Accelerated cardiac T2 mapping using breath-hold multiecho fast spin-echo pulse sequence with k-t FOCUSS.
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DOI：
10.1002/mrm.22756
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发表时间：
2011-06
影响因子：
3.3
通讯作者：
Kim, Daniel
中科院分区：
文献类型：
--
作者：
Feng, Li;Otazo, Ricardo;Jung, Hong;Jensen, Jens H.;Ye, Jong C.;Sodickson, Daniel K.;Kim, Daniel
心脏T2映射是对心肌水肿和铁超负荷的定量评估的有望方法。使用K-T焦点不确定的系统求解器（Pocuss）加速了这种新的ME-FSE脉冲序列，该框架使用了一个框架，该框架既利用压缩灵敏度和平行成像（.e.g，Grappa），以实现较高的空间分辨率。短轴平面并比较了使用ME-FSE与Grappa和Me-Fos与K-T焦点进行的T2测量的准确性。与使用grappa获得的T2测量值相比，在最终步骤中的稀疏转换和最终步骤组件分析中，使用K-T Pocuss获得的T2测量值非常一致（平均差异= 0.04 ms；上/下95％的95％限制一致性为2.26/-2.19 ms）。
Cardiac T2 mapping is a promising method for quantitative assessment of myocardial edema and iron overload. We have developed a new multi-echo fast spin echo (ME-FSE) pulse sequence for breath-hold T2 mapping with acceptable spatial resolution. We propose to further accelerate this new ME-FSE pulse sequence using k-t FOCal Underdetermined System Solver (FOCUSS) adapted with a framework that utilizes both compressed sensing and parallel imaging (.e.g, GRAPPA) to achieve higher spatial resolution. We imaged twelve control subjects in mid-ventricular short-axis planes and compared the accuracy of T2 measurements obtained using ME-FSE with GRAPPA and ME-FSE with k-t FOCUSS. For image reconstruction, we used a bootstrapping two-step approach, where in the first step fast Fourier transform was used as the sparsifying transform and in the final step principal component analysis was used as the sparsifying transform. Compared with T2 measurements obtained using GRAPPA, T2 measurements obtained using k-t FOCUSS were in excellent agreement (mean difference = 0.04 ms; upper/lower 95% limits of agreement were 2.26/−2.19 ms). The proposed accelerated ME-FSE pulse sequence with k-t FOCUSS is a promising investigational method for rapid T2 measurement of the heart with relatively high spatial resolution (1.7 mm × 1.7 mm).
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影响因子：
3.3
作者：
Sodickson, DK;Manning, WJ
通讯作者：
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作者：
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