CONTROL OF GENIOGLOSSUS MUSCLE INSPIRATORY ACTIVITY
CONTROL OF GENIOGLOSSUS MUSCLE INSPIRATORY ACTIVITY
复制标题
DOI：
10.1152/jappl.1980.49.5.801
复制
发表时间：
1980-01-01
影响因子：
3.3
通讯作者：
THACH, BT
中科院分区：
文献类型：
--
作者：
BROUILLETTE, RT;THACH, BT
记录 13 只麻醉兔子在无刺激呼吸期间的紧张性和阶段性吸气颏舌肌 (GG) 肌电图活动 (EMG)。集成 GG EMG 比集成膈肌 (DIA) EMG 更早在灵感中达到峰值，并且呈现出更圆润的轮廓。自发增强深吸气（叹气）在 GG 和 DIA EMG 中显示出双相模式。过度换气消除了 DIA 之前 GG 的阶段性吸气活动，表明 GG 具有较高的 CO2 呼吸暂停点。高碳酸血症增加肌电图； GG EMG 相对于基线的百分比比 DIA EMG 增加更多。 O2 呼吸对 GG 的影响大于 DIA EMG； NaCN 注射和短暂的 N2 呼吸使 GG 增加的幅度大于 DIA EMG；颈动脉体去神经术消除了这些反应。迷走神经切断术消除了两侧肌肉的 Hering-Breuer 膨胀抑制反射，并且触觉、视觉和听觉刺激使 GG 的增加多于 DIA EMG。 GG 对化学感受器输入和非特异性呼吸刺激的反应与 DIA 反应在性质上相似，但在数量上不同。讨论了与混合性和阻塞性呼吸暂停的相关性。
Tonic and phasic inspiratory genioglossus (GG) electromyographic activity (EMG) was recorded from 13 anesthetized rabbits during unstimulated breathing. Integrated GG EMG peaked earlier in inspiration and presented a more rounded contour than integrated diaphragmatic (DIA) EMG. Spontaneous augmented deep inspirations (sighs) showed a biphasic pattern in GG and DIA EMG. Hyperventilation abolished phasic inspiratory activity in the GG before the DIA, suggesting that the GG has a higher CO2 apneic point. Hypercapnia increased both EMG; GG EMG increased more, as a percent of base line, than did DIA EMG. O2 breathing decreased GG more than DIA EMG; NaCN injection and brief N2 breathing increased GG more than DIA EMG; carotid body denervation abolished these responses. Vagotomy abolished the Hering-Breuer inflation-inhibition reflex in both muscles, and tactile visual, and auditory stimulation increased GG more than DIA EMG. GG responses to chemoreceptor input and to nonspecific respiratory stimuli are qualitatively similar but quantitatively different from DIA responses. The relevance to mixed and obstructive apnea is discussed.