A New Fluorescent Chemodosimeter for Hg2+ : Selectivity, Sensitivity, and Resistance to Cys and GSH
A New Fluorescent Chemodosimeter for Hg2+ : Selectivity, Sensitivity, and Resistance to Cys and GSH
复制标题
新型 Hg2 荧光化学剂量计：对 Cys 和 GSH 的选择性、灵敏度和耐受性
DOI：
10.1021/ol902590g
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发表时间：
2010-02-05
期刊：
影响因子：
5.2
通讯作者：
Sun, Shiguo
中科院分区：
文献类型：
--
作者：
Du, Jianjun;Fan, Jiangli;Sun, Shiguo
根据Hg 2+促进水解的机理，研制了一种新的荧光化学剂量计（Rho-Hg 1），可用于沃茨中Hg 2+的单选择性和十亿分之一灵敏度的检测。Rho-Hq 1对Hg ~（2+）的荧光响应几乎不受半胱氨酸和谷胱甘肽等含硫化合物的干扰，可用于活细胞中Hg ~（2+）的成像。
On the basis of the mechanism of Hg2+-promoted hydrolysis, a new fluorescent chemodosimeter (Rho-Hg1) is reported for single-selective and parts per billion level-sensitive detection of Hg2+ in natural waters. Moreover, the fluorescence response of Rho-Hq1 to Hg2+ has little interference from sulfur compounds such as cysteine and glutathione and could be used in the Hg2+ imaging in living cells.