Modeling SF3B1 Mutations in Cancer: Advances, Challenges, and Opportunities.
Modeling SF3B1 Mutations in Cancer: Advances, Challenges, and Opportunities.
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建模癌症中的SF3B1突变:进步,挑战和机遇。
DOI:
10.1016/j.ccell.2016.08.013
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发表时间:
2016-09-12
期刊:
影响因子:
50.3
通讯作者:
Abdel-Wahab O
中科院分区:
文献类型:
--
作者:
Inoue D;Abdel-Wahab O
In this issue of Cancer Cell, Obeng et al. identify the consequences of expressing the most common mutation in the spliceosomal gene SF3B1 on hematopoiesis. The knockin mouse model described represents a valuable tool to dissect the effects of SF3B1 mutations on transformation, splicing, and less well-characterized functions of SF3B1.
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影响因子:
5.3
作者:
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通讯作者:
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