By their powers combined, global initiative joins forces for genomic research.
By their powers combined, global initiative joins forces for genomic research.
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通过联合力量，全球倡议联合起来进行基因组研究。
DOI：
10.1016/j.cell.2022.10.010
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发表时间：
2022
期刊：
影响因子：
64.5
通讯作者：
Wojcik,GenevieveL
中科院分区：
文献类型：
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作者：
Wojcik,GenevieveL
全基因组关联研究 (GWAS) 可能需要大量样本才能识别整个频谱中与人类健康相关的变异。作为全球生物样本库荟萃分析计划 (GBMI)，Zhou 等人。描述了一个跨 23 个生物库和 220 万参与者的协作网络，以解决基因组研究多样性代表性不足的挑战。
Genome-wide association studies (GWASs) can require immense sample sizes to identify variants associated with human health across the frequency spectrum. As the Global Biobank Meta-analysis Initiative (GBMI), Zhou et al. describe a collaborative network across 23 biobanks and 2.2 million participants to address challenges of underrepresentation of diversity in genomic research.