OUDEMANSIN, STROBILURIN-A, STROBILURIN-B AND MYXOTHIAZOL - NEW INHIBITORS OF THE BC1 SEGMENT OF THE RESPIRATORY-CHAIN WITH AN E-BETA-METHOXYACRYLATE SYSTEM AS COMMON STRUCTURAL ELEMENT
OUDEMANSIN, STROBILURIN-A, STROBILURIN-B AND MYXOTHIAZOL - NEW INHIBITORS OF THE BC1 SEGMENT OF THE RESPIRATORY-CHAIN WITH AN E-BETA-METHOXYACRYLATE SYSTEM AS COMMON STRUCTURAL ELEMENT
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DOI：
10.1016/0014-5793(81)81190-8
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发表时间：
1981-01-01
期刊：
影响因子：
3.5
通讯作者：
STEGLICH, W
中科院分区：
文献类型：
--
作者：
BECKER, WF;VONJAGOW, G;STEGLICH, W
新型抗真菌抗生素myxothiazol的抑制作用和结合特性在文献[1,2]中有描述。像抗霉素一样，粘噻唑结合非常紧密，完全抑制电子流动，滴度为1 mol抑制剂/m01复合物III。然而，粘噻唑与抗霉素以外的位点结合，如铁细胞色素b光谱的红移所示。粘噻唑的红移独立于抗霉素红移，与抗霉素红移不同。myxothlazol
The inhibitory action and binding characteristics of the new anti-fungal antibiotic myxothiazol has been described in [1, 2]. Like antimycin, myxothiazol binds very tightly, inhibiting the electron flow completely at a titer of-1 mol inhibitor/m01 complex III. However, myxothiazol binds to a site other than that of antimycin, as indicated by a red shift of the ferrocytochrome b spectrum. The myxothiazol shift is independent of and differs from the antimycin red shift. myxothlazol