INTRACORONARY STENTING WITHOUT ANTICOAGULATION ACCOMPLISHED WITH INTRAVASCULAR ULTRASOUND GUIDANCE

INTRACORONARY STENTING WITHOUT ANTICOAGULATION ACCOMPLISHED WITH INTRAVASCULAR ULTRASOUND GUIDANCE
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DOI:
10.1161/01.cir.91.6.1676
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发表时间:
1995-03-15
期刊:
影响因子:
37.8
通讯作者:
TOBIS, JM
TOBIS, JM
中科院分区:
医学1区
文献类型:
--
作者:
COLOMBO, A;HALL, P;TOBIS, JM

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背景:与球囊血管成形术相比,冠状动脉内支架置入术可减少再狭窄。然而,冠状动脉内支架的临床使用受到亚急性支架血栓形成和与抗凝方案相关的并发症的风险的阻碍。为了减少这些并发症,假设系统抗凝治疗是没有必要的,当足够的支架扩张是实现了前瞻性的连续一系列的患者接受intracoronary stents.Methods和结果从1993年3月至1994年1月,359例患者进行了Palmaz-Schatz冠状动脉支架插入。在最初成功的血管造影结果后,
Background The placement of stents in coronary arteries has been shown to reduce restenosis in comparison to balloon angioplasty. However, clinical use of intracoronary stents is impeded by the risk of subacute stent thrombosis and complications associated with the anticoagulant regimen. To reduce these complications, the hypothesis that systemic anticoagulation is not necessary when adequate stent expansion is achieved was prospectively evaluated on a consecutive series of patients who received intracoronary stents.Methods and Results From March 1993 to January 1994, 359 patients underwent Palmaz-Schatz coronary stent insertion. After an initial successful angiographic result with