Isotropic diffusion weighting in radial fast spin-echo magnetic resonance imaging

Isotropic diffusion weighting in radial fast spin-echo magnetic resonance imaging
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DOI:
10.1002/mrm.20493
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发表时间:
2005-06-01
影响因子:
3.3
通讯作者:
Trouard, TP
Trouard, TP
中科院分区:
医学3区
文献类型:
--
作者:
Sarlls, JE;Newbould, RD;Trouard, TP

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径向快速自旋回波(RADIUS-FSE)方法使多次激发扩散加权磁共振成像(DWMRI)不会因运动和/或敏感性而产生明显伪影,并可用于生成高空间分辨率的DWMRI图像。在这项工作中,提出了一种新的方法,允许在单个径向k空间数据集中获得各向同性扩散加权。这是通过改变TR周期组之间的扩散加权梯度的方向来实现的,这产生了对不同方向上的运动敏感的具有扩散加权的径向线集合。通过改变扩散加权方向和适当控制序列内的视图排序,可以在一次径向FSE扫描内获得有效的各向同性扩散加权图像。还可以控制获取径向线的顺序,以产生没有由于运动、T-2衰减和/或扩散各向异性引起的显著伪影的数据集。(C)2005年Wiley-Liss,Inc.
Radial fast spin-echo (radial-FSE) methods enable multishot diffusion-weighted MRI (DWMRI) to be carried out without significant artifacts due to motion and/or susceptibility and can be used to generate DWMRI images with high spatial resolution. In this work, a novel method that allows isotropic diffusion weighting to be obtained in a single radial k-space data set is presented. This is accomplished by altering the direction of diffusion weighting gradients between groups of TR periods, which yield sets of radial lines that possess diffusion weighting sensitive to motion in different directions. By altering the diffusion weighting directions and controlling the view ordering appropriately within the sequence, an effectively isotropic diffusion-weighted image can be obtained within one radial-FSE scan. The order in which radial lines are acquired can also be controlled to yield data sets without significant artifacts due to motion, T-2 decay, and/or diffusion anisotropy. (c) 2005 Wiley-Liss, Inc.