CROSS-LINKED FIBRINOGEN DIMERS DEMONSTRATE A FEATURE OF THE MOLECULAR PACKING IN FIBRIN FIBERS
CROSS-LINKED FIBRINOGEN DIMERS DEMONSTRATE A FEATURE OF THE MOLECULAR PACKING IN FIBRIN FIBERS
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DOI：
10.1126/science.6108612
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发表时间：
1981-01-01
期刊：
影响因子：
56.9
通讯作者：
HERMANS, J
中科院分区：
文献类型：
--
作者：
FOWLER, WE;ERICKSON, HP;HERMANS, J
制备由[人]因子XIIIa交联的纤维蛋白原二聚体的稳定群体，并通过EM进行检查。三结节纤维蛋白原分子通过其外部结节以端对端、非重叠的方式交联。这些二聚体在用凝血酶凝血酶处理后形成正常的带状纤维。
A stable population of fibrinogen dimers cross-linked by [human] factor XIIIa was prepared and examined by EM. The trinodular fibrinogen molecules are cross-linked through their outer nodules in an end-to-end, non-overlapping fashion. These dimers form normal banded fibers after treatment with the clotting enzyme, thrombin.