Sambamba: fast processing of NGS alignment formats.

Sambamba: fast processing of NGS alignment formats.
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DOI:
10.1093/bioinformatics/btv098
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发表时间:
2015-06-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
通讯作者:
Prins P
Prins P
中科院分区:
其他
文献类型:
--
作者:
Tarasov A;Vilella AJ;Cuppen E;Nijman IJ;Prins P

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摘要:Sambamba是一个高性能、强大的工具和库,用于处理SAM、BAM和CRAM序列比对文件;是用于比对下一代测序数据的最常见的文件格式。Sambamba是利用多核处理并显著减少处理时间的SamTools的更快的替代方案。Sambamba正被测序中心采用,这不仅是因为它的速度,还因为它的附加功能,包括覆盖分析和强大的过滤能力。可获得性和实现:Sambamba是免费的开源软件,在GPLv2许可下可用。可从http://www.open-bio.org/wiki/Sambamba.下载和安装SambambaSambamba v0.5.0是通过doi:10.5281/zenod.13200发布的。联系人:j.c.p.prins@umcutrecht.nl
Summary: Sambamba is a high-performance robust tool and library for working with SAM, BAM and CRAM sequence alignment files; the most common file formats for aligned next generation sequencing data. Sambamba is a faster alternative to samtools that exploits multi-core processing and dramatically reduces processing time. Sambamba is being adopted at sequencing centers, not only because of its speed, but also because of additional functionality, including coverage analysis and powerful filtering capability. Availability and implementation: Sambamba is free and open source software, available under a GPLv2 license. Sambamba can be downloaded and installed from http://www.open-bio.org/wiki/Sambamba. Sambamba v0.5.0 was released with doi:10.5281/zenodo.13200. Contact: j.c.p.prins@umcutrecht.nl