Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices
Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices
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DOI：
10.3390/mi9030115
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发表时间：
2018-03-01
期刊：
影响因子：
3.4
通讯作者：
Rapp, Bastian E.
中科院分区：
文献类型：
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作者：
Kotz, Frederik;Risch, Patrick;Rapp, Bastian E.
高度氟化的全氟聚醚（PFPE）甲基丙烯酸酯对于透明且耐化学腐蚀的微流控芯片具有重大意义。然而，到目前为止，这些聚合物用于三维（3D）打印的材料配方仅有少数几个实例得到了验证。在本文中，我们展示了可以通过3D立体光刻打印技术使用这些高度氟化的聚合物来打印微流控芯片。我们开发了可在商用台式立体光刻打印机中打印的光固化树脂配方。我们证明，所开发的配方对于整体嵌入式微流控通道，最小横截面积可打印至600微米，对于开放式结构可打印至200微米。打印并聚合的PFPE甲基丙烯酸酯在520 - 900纳米波长范围内显示出超过70%的良好透光率，并且在接触有机溶剂时具有高耐化学性。我们打印了微流控混合器，以展示使用立体光刻技术可打印的不同设计的高度多样性。
Highly fluorinated perfluoropolyether (PFPE) methacrylates are of great interest for transparent and chemically resistant microfluidic chips. However, so far only a few examples of material formulations for three-dimensional (3D) printing of these polymers have been demonstrated. In this paper we show that microfluidic chips can be printed using these highly fluorinated polymers by 3D stereolithography printing. We developed photocurable resin formulations that can be printed in commercial benchtop stereolithography printers. We demonstrate that the developed formulations can be printed with minimal cross-sectional area of 600 mu m for monolithic embedded microfluidic channels and 200 mu m for open structures. The printed and polymerized PFPE methacrylates show a good transmittance above 70% at wavelengths between 520-900 nm and a high chemical resistance when being exposed to organic solvents. Microfluidic mixers were printed to demonstrate the great variability of different designs that can be printed using stereolithography.