The adsorption of O2 of the resting and workin skeletal muscles

The adsorption of O2 of the resting and workin skeletal muscles
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DOI:
10.1111/j.1748-1716.1939.tb00462.x
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发表时间:
1939-01-01
期刊:
SKANDINAVISCHES ARCHIV FUR PHYSIOLOGIE
影响因子:
--
通讯作者:
Nielsen, M
Nielsen, M
中科院分区:
其他
文献类型:
--
作者:
Asmussen, E;Christensen, EH;Nielsen, M

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通过大腿周围的充气袖带(压力300毫米汞柱)阻断双腿的血液循环降低了10%的静息代谢这10%显然与下肢的正常静息代谢相对应,并且在估计体重后。在腿部肌肉中,发现人肌肉的静息代谢为1.7cc。O2/kg./最小值或0.5卡/千克/ hr。在骑自行车工作期间,发现50%的额外O2摄入量被腿部利用,并计算出在调查的最艰苦工作期间(1080 kg./(最小值)肌肉的新陈代谢是112 cc。O2/kg./最小,也就是说,增加到静息值的64倍。通过外推法发现,在最大工作期间,人体肌肉的O2-摄入量增加了100倍以上的静息代谢。通过最大限度工作的肌肉的血液循环必须相应地增加至少50倍的休息循环。
Blocking the circulation to both legs by means of inflated cuffs around the thighs (pressure 300 mm.Hg.) lowered the resting metabolism by about 10%. This 10% apparently corresponded to the normal resting metabolism of the lower extremities, and after an estimation of the wt. of the muscles of the legs the resting metabolism of human muscles was found to be 1.7 cc. O2 per kg./min. or 0.5 Cal. per kg./hr. During work on the bicycle it was found that 50% of the extra O2 intake was utilized by the legs, and it was calculated that during the hardest work investigated (1080 kg./min.) the metabolism of the muscles was 112 cc. O2 per kg./min., i.e., an increase to 64 times the resting value. By extrapolation it was found that during maximal work the O2-intake of human muscles increased more than 100 times their resting metabolism. The circulation of blood through maximally working muscles must correspondingly be increased by at least 50 times the resting circulation.