A PCR-RFLP typing method for adhesion molecule gene polymorphisms and allele frequencies in a normal UK population

A PCR-RFLP typing method for adhesion molecule gene polymorphisms and allele frequencies in a normal UK population
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DOI:
10.1046/j.1365-2370.2002.00277.x
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发表时间:
2002-04-01
期刊:
EUROPEAN JOURNAL OF IMMUNOGENETICS
影响因子:
--
通讯作者:
Webb, NJA
Webb, NJA
中科院分区:
其他
文献类型:
--
作者:
Gbadegesin, RA;Watson, CJ;Webb, NJA

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We report simple and reproducible PCR-RFLP typing methods for the polymorphisms in the ICAM-1, E-selectin and PECAM-1 genes. The genotype and allele frequencies detected in a normal UK population did not deviate significantly from the Hardy-Weinberg equilibrium; neither did they differ from frequencies previously reported. using SSP or SSCP methods.