Spiraling steroids: organic crystals with asymmetric nanometer-scale channels.
Spiraling steroids: organic crystals with asymmetric nanometer-scale channels.
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螺旋类固醇：具有不对称纳米级通道的有机晶体。
DOI：
10.1002/anie.200502330
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发表时间：
2005
影响因子：
--
通讯作者：
A. Davis
中科院分区：
文献类型：
--
作者：
Adam L. Sisson;Vicente del Amo Sanchez;G. Magro;A. Griffin;Shilen Shah;J. Charmant;A. Davis
结晶微孔（或纳米多孔）固体被广泛地寻求和研究。[1]这种材料为晶体工程提供了挑战，并在催化、分离技术、气体储存、传感器、激光器等方面找到了应用。具有大空隙的坚固结构特别有趣，因为它们能够容纳最广泛的客人。渠道，衡量！直径1纳米在无机[1a-c]材料中相当常见，尤其是金属有机骨架（MOF）[1c-g]材料。然而，具有这种尺寸的纯有机结构很少见，特别是如果排除大环分子的话。[2]我们现在报告一类新的纳米多孔有机晶体与手性，单向通道，可调的直径超过14。这一发现源于我们对类固醇阴离子受体的研究。[3]“胆足”1属于一系列衍生自胆酸2的化合物，其中氢-
Crystalline microporous (or nanoporous) solids are widely sought and studied.[1] Such materials provide challenges for crystal engineering and find applications in catalysis, separation techniques, gas storage, sensors, lasers, and so forth. Robust structures with large voids are especially interesting, as they are able to accommodate the widest range of guests. Channels that measure! 1 nm in diameter are fairly common in inorganic [1a–c] and, especially, metal–organic-framework (MOF)[1c–g] materials. However, purely organic structures with such dimensions are rare, especially if macrocyclic molecules are excluded.[2] We now report a new class of nanoporous organic crystals with chiral, unidirectional channels, tunable to diameters in excess of 14. This discovery arose from our program on steroid-based anion receptors.[3] The “cholapod” 1 belongs to a series of compounds derived from cholic acid 2, in which hydrogen-