DIETARY RESTRICTION REDUCES FLUORESCENT AGE PIGMENT ACCUMULATION IN MICE
DIETARY RESTRICTION REDUCES FLUORESCENT AGE PIGMENT ACCUMULATION IN MICE
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DOI：
10.1016/0531-5565(81)90056-5
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发表时间：
1981-01-01
影响因子：
3.9
通讯作者：
KRUK, P
中科院分区：
文献类型：
--
作者：
ENESCO, HE;KRUK, P
研究人员在 3、5、7 和 12 个月的雄性瑞士白化小鼠的大脑和心脏中检查了脂质过氧化荧光产物（或脂褐质）的饮食限制的影响。的年龄。与所有年龄组的对照小鼠相比，限制饮食的小鼠大脑中荧光产物的水平显着降低。到了12个月。随着年龄的增长，与对照组小鼠相比，限制饮食的小鼠心脏组织中脂质过氧化荧光产物的水平显着降低。饮食限制可能通过降低游离放射反应水平来延缓脂褐质积累。
The influence of dietary restriction of lipid peroxidation fluorescent products, or lipofuscin, was examined in brain and heart in male Swiss albino mice at 3, 5, 7 and 12 mo. of age. The level of fluorescent products was significantly lower in the brain of mice on the restricted diet as compared to control mice in all age groups. By 12 mo. of age, the level of lipid peroxidation fluorescent products was significantly lower in the heart tissue of mice on the restricted diet as compared to control mice. Dietary restriction may retard lipofuscin accumulation by reducing the level of free radial-reactions.