Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter.
Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter.
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亲嗜性宿主范围小鼠逆转录病毒的细胞表面受体:一种阳离子氨基酸转运蛋白。
DOI:
10.1007/978-3-7091-9326-6_47
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发表时间:
1994
期刊:
影响因子:
--
通讯作者:
Kabat,D
中科院分区:
文献类型:
--
作者:
Kavanaugh,MP;Wang,H;Boyd,CA;North,RA;Kabat,D
The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.