Parents' attitudes to children's participation in randomized controlled trials
Parents' attitudes to children's participation in randomized controlled trials
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DOI：
10.1067/mpd.2003.192
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发表时间：
2003-05-01
影响因子：
5.1
通讯作者：
Craig, JC
中科院分区：
文献类型：
--
作者：
Caldwell, PHY;Butow, PN;Craig, JC
目的探讨家长对儿童参与随机对照试验的态度。研究设计对来自澳大利亚儿科教学医院和当地学校的33名家长进行焦点小组讨论的定性分析。父母的年龄、性别、种族、教育水平、研究经验和孩子的健康状况各不相同。使用持续比较方法按主题链接对记录的讨论进行分析。 结果 父母在决定让孩子参加试验时平衡风险和收益，感知到的好处包括提供希望、更好地照顾孩子、获得新治疗方法、医疗保健专业人员和健康信息的机会、与处于类似情况的其他人见面以及帮助他人。感知的风险包括潜在的副作用、随机接受无效的治疗以及参与的不便。参与试验的决定还受到父母因素（父母的知识、信仰和情绪反应）、儿童因素（孩子的健康状况和参与偏好）、试验因素（安慰剂的使用和参与的不确定性）和医生因素（医生的建议和试验信息的沟通）的影响。家长参与试验的意愿。
Objective To explore parents' attitudes to children's participation in randomized controlled trials.Study design Qualitative analysis of focus group discussions involving 33 parents from a pediatric teaching hospital and local school in Australia. Parents varied in age, gender, ethnicity, level of education, research experience, and child's health status. The transcribed discussions were analyzed by theme linkage using the constant comparative method.Results Parents balance risks and benefits when deciding about trial participation for their child, Perceived benefits include the offer of hope, better care of their child, the opportunity to access new treatments, healthcare professionals and health information, meeting others in similar circumstances, and helping others. Perceived risks include potential side effects, being randomized to ineffective treatments, and the inconvenience of participation. The decision for trial participation is also influenced by parental factors (parents' knowledge, beliefs, and emotional responses), child factors (the child's health status and preference about participation), trial factors (the use of placebos and uncertainties of participation), and doctor factors (doctor's recommendations and communication of trial information).Conclusions Educating parents about trials, improving communication between trialists, pediatricians, and parents, increasing incentives while decreasing inconveniences, and providing decision aids for parents may increase parents' willingness to participate in trials.