Effect of interfacial tension on flow of fluorochemicals in the vasculature of the lung: a theoretical and experimental study.
Effect of interfacial tension on flow of fluorochemicals in the vasculature of the lung: a theoretical and experimental study.
复制标题
界面张力对肺血管系统中含氟化合物流动的影响：理论和实验研究。
DOI：
10.1007/bf02368451
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发表时间：
1990
影响因子：
3.8
通讯作者：
Noordergraaf,A
中科院分区：
文献类型：
--
作者：
Saadi-Elmandjra,M;Joseph,PM;Noordergraaf,A
全氟碳化合物可以使用磁共振进行选择性成像。当引入脉管系统时，它们不会流动超过一定水平。这取决于驱动压力。我们在这里考虑这种流动停止的情况下，血管床的大鼠肺。基于界面张力是导致这种现象的主要原因的假设的理论分析得出了一个公式，该公式预测了流动停止处的容器的“临界”半径。该半径取决于驱动压力。预测的结果进行了实验验证，使用直接测量的组织切片，并证实了这一假设。
Perfluorocarbons can be selectively imaged using magnetic resonance. When introduced in the vasculature they do not flow beyond a certain level. This level depends on the driving pressure. We consider here such flow stoppage in the case of the vascular bed of rat lung. A theoretical analysis based on the assumption that interfacial tension is primarily responsible for this phenomenon leads to a formula that predicts a “critical” radius of the vessels at where the flow stops. This radius depends on the driving pressure. The predicted result was verified experimentally using direct measurements on histological sections and was found to confirm the hypothesis.