Depressive symptoms and metabolic control in African-Americans with type 2 diabetes
Depressive symptoms and metabolic control in African-Americans with type 2 diabetes
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DOI：
10.2337/diacare.23.1.23
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发表时间：
2000-01-01
期刊：
影响因子：
16.2
通讯作者：
Cooper-Patrick, L
中科院分区：
文献类型：
--
作者：
Gary, TL;Ford, D;Cooper-Patrick, L
目的-以确定抑郁症状的患病率和抑郁症状和代谢control.RESEARCH设计和方法之间的关系-我们进行了一项横断面研究的183名非洲裔美国成年人年龄在35-75岁的2型糖尿病患者从两个初级保健诊所在东巴尔的摩，马里兰州招募。使用流行病学研究中心抑郁量表（CES-D）、HbA（1c）、空腹血脂、BMI和血压对每位参与者进行测量。糖尿病相关的健康行为进行了评估问卷调查。结果-抑郁症状（CES-D大于或等于22）的患病率为30%。经年龄、性别、经济收入、社会支持、糖尿病病程等因素校正后，抑郁症状越严重，血清胆固醇、甘油三酯水平越高（P < 0.050）。尽管统计学意义较小，但与HbA（1c）（P = 0.104）、舒张压（P = 0.073）和LDL胆固醇（P = 0.176）水平较高的关系相似。出乎意料的个人谁报告更多的抑郁症状也有更高的血清高密度脂蛋白胆固醇水平（P = 0.047），该协会没有解释的差异，糖尿病相关的健康behaviors.CONCLUSIONS-抑郁症状与次优水平的HbA（1C），舒张压，和低密度脂蛋白胆固醇，并显着相关的次优水平的总胆固醇和甘油三酯水平。需要进行前瞻性研究，以确定改善抑郁症状的识别和管理是否会提高这一人群的代谢控制。
OBJECTIVE- To determine the prevalence of depressive symptoms and the relationship between depressive symptoms and metabolic control.RESEARCH DESIGN AND METHODS- We conducted a cross-sectional study of 183 African-American adults aged 35-75 years with type 2 diabetes who were recruited from two primary care clinics in East Baltimore, Maryland. Depressive symptoms, using the Center for Epidemiological Studies Depression Scale (CES-D), HbA(1c), fasting lipid profile, BMI, and blood pressure, were measured on each participant. Diabetes-related health behaviors were assessed by questionnaire.RESULTS- The prevalence of depressive symptoms (CES-D greater than or equal to 22) was 30%. After adjust ment for age, sex, income, social support, and duration of diabetes in linear regression models, there were significant graded relationships between greater depressive symptoms and higher serum levels of cholesterol and triglycerides (P < 0.050). Similar, albeit less statistically significant, relationships were found with higher levels of HbA(1c) (P = 0.104), diastolic blood pressure (P = 0.073), and LDL cholesterol (P = 0.176). Unexpectedly individuals who reported more depressive symptoms also had higher serum levels of HDL cholesterol (P = 0.047), The associations were not explained by differences in diabetes-related health behaviors.CONCLUSIONS- Depressive symptoms are marginally associated with suboptimal levels of HbA(1c), diastolic blood pressure, and LDL cholesterol, and significantly associated with suboptimal levels of total cholesterol and triglyceride levels. Prospective studies are required to determine whether improved identification and management of depressive symptoms would enhance metabolic control in this population.