Measuring Cerebellar Function
Measuring Cerebellar Function
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测量小脑功能
DOI：
10.1007/978-1-0716-2026-7_4
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Apps R
中科院分区：
文献类型：
--
作者：
Apps R
小脑的一个关键组织特征是它分为一系列小脑模块。每个模块的皮层组成部分被称为一个区域。每个区域的爬升输入都是由下橄榄的一个明确的区域定义的，下橄榄的目标是小脑皮层内浦肯野细胞的一个或多个纵向区域。反过来，每个区域内的浦肯野细胞投射到小脑和前庭核的特定区域。区域的行为意义仍然知之甚少。本章将描述在急性和慢性准备（大鼠和猫）中从生理学和解剖学上识别小脑皮质带的方法，以及在行为过程中记录区域的方法，以确定它们在小脑功能中的作用。
A key organizational feature of the cerebellum is its division into a series of cerebellar modules. The cortical component of each module is termed a zone. Each zone is defined by its climbing input originating from a well-defined region of the inferior olive, which targets one or more longitudinal zones of Purkinje cells within the cerebellar cortex. In turn, Purkinje cells within each zone project to specific regions of the cerebellar and vestibular nuclei. The behavioral significance of zones remains poorly understood.This chapter will describe approaches to physiologically and anatomically identify cerebellar cortical zones in both acute and chronic preparat ions (rat and cat) as well as methods to record from zones during behavior in order to determine the role that they have in cerebellar function.