Spontaneous redistribution of surface immunoglobulin in the motile B lymphocyte.

Spontaneous redistribution of surface immunoglobulin in the motile B lymphocyte.
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DOI:
10.1084/jem.144.6.1683
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发表时间:
1976-12-01
期刊:
The Journal of experimental medicine
影响因子:
--
通讯作者:
Unanue ER
Unanue ER
中科院分区:
其他
文献类型:
--
作者:
Schreiner GF;Braun J;Unanue ER

文献摘要

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本文报道了B细胞在运动过程中自发地将其表面的IG分离到其质膜的一部分。表面IG的自发再分布被认为是:(a)选择性的,刀豆球蛋白A依赖于消化运动和能量代谢。丰富的B细胞进行运动后,发现在脂多糖或胰蛋白酶,或短暂暴露于胆碱能药物的文化。
This paper reports that B cells undergoing translatory motion spontaneously segregate their surface Ig to one portion of their plasma membrane. The spontaneous redistribution of surface Ig was found to be: (a) selective, concanavalin A-dependent on translatory motion and energy metabolism. Abundant B cells undergoing motility were found after cultures in lipopolysaccharide or trypsin, or after brief exposure to cholinergic drugs.