Presence of phosphatidylserine in the outer membrane bilayer of newborn human erythrocytes.
Presence of phosphatidylserine in the outer membrane bilayer of newborn human erythrocytes.
复制标题
新生红细胞外膜双层中存在磷脂酰丝氨酸。
DOI：
10.1016/0006-291x(86)90419-5
复制
发表时间：
1986
影响因子：
3.1
通讯作者：
Jain,SK
中科院分区：
文献类型：
--
作者：
Jain,SK
红细胞膜双层的磷脂分布是不对称的。鞘磷脂和磷脂酰胆碱主要存在于外膜双层中，而只有少量的磷脂酰乙醇胺和没有磷脂酰丝氨酸存在于外膜双层中。目前的研究，使用特定的磷脂酶，化学探针，和罗素的蝰蛇毒液凝血时间发现，在新生儿红细胞的PS的一部分也存在于外膜双层。
The phospholipid distribution across red cell membrane bilayer is asymmetrical. Sphingomyelin and phosphatidylcholine are predominantly present in the outer membrane bilayer, whereas only small amounts of phosphatidylethanolamine and no phosphatidylserine are present in the outer membrane bilayer. The present study, using specific phospholipase, chemical probe, and Russell's viper venom clotting time has found that in neonatal red cells a portion of PS is also present in the outer membrane bilayer.