Subthreshold symptoms in bipolar disorder: Impact on neurocognition, quality of life and disability
Subthreshold symptoms in bipolar disorder: Impact on neurocognition, quality of life and disability
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DOI：
10.1016/j.jad.2011.10.012
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发表时间：
2012-02-01
影响因子：
6.6
通讯作者：
Torrent, C.
中科院分区：
文献类型：
--
作者：
Bonnin, C. M.;Sanchez-Moreno, J.;Torrent, C.
目的：提供阈下症状（抑郁和躁狂）对双相情感障碍心理社会功能、神经认知和生活质量影响的经验证据。 方法：本研究共有 133 名参与者（双相情感障碍患者，n = 103；健康对照，n = 30）。根据阈下症状水平将患者分为两组：亚症状组由阈下症状水平较高的患者（HDRS >= 4 和 YMRS >= 3）组成，无症状组由阈下症状水平较低的患者（HDRS >= 3）组成。
Objective: To provide empirical evidence of the effect of subthreshold symptomatology (both depressive and manic) on psychosocial functioning, neurocognition and quality of life in bipolar disorder.Methods: A total of 133 participants were enrolled for this study (bipolar patients, n = 103; healthy controls, n = 30). Patients were divided into two groups according to their levels of subthreshold symptomatology: the subsyndromic group was constituted by those patients with upper levels of subthreshold symptomatology (HDRS >= 4 and YMRS >= 3) and the asymptomatic group represented the patients with lower scores (HDRS